Insulin Resistance – Pre Diabetics

Hello readers,

I am back with another article related to health & Fitness. If you have not checked my previous one on intro to fat building, please check the article in below link,

https://mrawesomevs.wordpress.com/2018/01/05/fat-building-intro/

In this article, we will look in to what is insulin resistance, why it is caused, how it can be prevented.

Insulin is a hormone produced by pancreases when glucose level in blood increases. It is main anabolic ( i.e. builds body)  hormone.

Purpose of Insulin

Insulin is the key factor for cells to absorb glucose for energy purpose. without insulin, body cells will be starved without food particles , leading to many health issues.

Where is Insulin produced

Pancreases is the organ that produces insulin.  Endocrine tissues do this task.Pancreases also has another task related to digestion. It produces enzymes that help in digestion of food.

Insulin is produced by specific cells, called Beta cells of pancreases, when the sugar level in the blood is high. These Beta cells are sensitive to glucose concentrations. Once they detect high glucose level, they release insulin, which helps in glucose absorption by cells.

 

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Once the glucose level is dropped in blood, these Beta cells stop producing insulin. Their neighboring alpha cells, by taking their cues from the Beta cells, secrete Glucagon ( works opposite of Insulin ) into the blood.

Insulin Working

Once Insulin is released in to blood, it binds with cells to facilitate glucose transfer in to Muscle cells for proper functioning of cells as Glycogen. If there is any excess glucose is present, it will be saved in to Liver.  Still if there is any excess glucose, it will be stored into fat cells.

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Schematic two-dimensional cross-sectional view of glycogen: A core protein of glycogenin is surrounded by branches of glucose units. The entire globular granule may contain around 30,000 glucose units. Courtesy : Google.

Role of physical activity

Physical activity such as weight training/ resistance training, cardio etc. will use the glycogen stored in muscle cells & Liver.  If we do work out regularly the glycogen stores gets depleted after workout and again refilled after meals.  If we dont do any physical activity, the glycogen stores remain same and all the glucose entered in the blood will be stored as fat ( not good !!). This also results in fatty liver issues & Insulin Resistance

Insulin Resistance

The process of Insulin secretion, food absorption by cells takes place every time we eat something.  Without much physical activity , the glycogen reserves in cells remain unaffected. Therefore the cells dont need any external glucose to survive. This implies they dont need insulin for glucose transfer.

Also high carbs diets results in insulin peaks, which makes insulin to last longer in blood than normal diet. Continuously eating also results in sustained insulin levels in body. As a results cells do not respond well to insulin, as it is always present in body. So to make cells absorb glucose, excess insulin is required to make cells respond to insulin and absorb glucose. Over period this situation develops in to Type -2 Diabetics. If pancreases is unable to produce the necessary insulin for glucose transfer, it results in to type -1 diabetics.

Prevention

Physical activity and proper diet helps to increase insulin sensitivity of cells. Resistance training is excellent for depleting glycogen reserves stored in muscle cells and replenish cells with proper mix of carbs, protein & fats.

Wish you a peaceful and lovely life ahead 🙂

 

 

 

 

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Fat building – Intro

Hey there,

I have been going to gym for quite a time and I did some research from my end on how our human body works with muscle building & fat burning. I wanted to share my understanding on these topics with you guys in this article.

What happens to food we eat ?

Some of us like sweets, some of us spicy foods and all of like food that tastes yummy and feels like heaven while it lasts in out mouth.

Once the food is pushed back from mouth to stomach, the acids produced by stomach will break down the food in to tiny particles. Also the acid serves another purpose : to kill all bacteria , fungus etc  in our food. Food will typical stay in 2 – 5 hours depending on nature. simple Carbohydrates like white rice , white bread, fruit juices will be stay around 1 – 2 hr, while complex items like proteins, fats and fibers will stay for 2- 5 hrs in stomach.

What’s next ?

Once stomach finishes its job, the food particles move to small intestine via a small duct. The food coming from stomach is highly acidic in nature and it would wipe out most of fauna in intestine. So to compensate the acidic nature of food, Liver / Gall bladder will produce bile which is alkaline in nature. It will also help in digestion of fats.

Enzymes produced in  small intestine, Liver, pancreases will break down the food particles. The Bactria in small intestine also produces enzymes that breaks down complex proteins in to basic amino acids.

As the food passes through small intestine, digested particles will be absorbed in to blood via  intestine walls.

Now comes the important task:

Once the digested food (typically glucose) enters blood, there by increasing the glucose concentration in blood.

Glucose cannot be directly absorbed by cells. Cells need specific task performer called “Insulin” to do the task. Once the glucose level increases, Pancreases releases Insulin, which will bind with cells and there by providing a channel for glucose t enter in to our cells for energy purpose.

insulin

This insulin spike will last for 2 – 4 hours typically depending on glucose level and insulin sensitivity of cells.

Insulin also has one more important task apart from supplying glucose to cells. It promotes synthesis of fat.

Once glucose enters to blood, first all glucose will be supplied to cells. Muscle cells stores the glucose in form of Glycogen. This will approximately 1600 -1700 Calories. Remaining glucose up to 400 calories will be stored in Liver in form of Glycogen.  The excess glucose will be stored in to fat cells in form of fatty acids. If this storage of excess glucose continues for months, then the person develops belly fat, love handles , chest fat etc.

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Catching up with Cats

It’s been 2 months since I met my cat friends . Converting to cat -human time scales, it like 2.5

When I visited last time, there were few kittens , but this time kittens have out numbered adult cats.

Friend cat :

Simba:

She should be named as Nala,  considering her gender 😹

I am changing her name to “Sim” 😀

Sim has given birth to 2 beautiful and healthy kittens.

Sim’s lil kitten 1:

Sim’s lil kitten 2 :

Lil kitten drags empty Whiskas packet. Sim watches over her kittens actions.

Lil kitten : Grrrr,  this is mine 😼

Cousin cat :

Last time I visited cats, I missed Cousin cat. Now happy to see cousin cat 😀

Gunda Cat:

With tons of experience and age, he stands still for the shot .

Queen cat :

Seems queen cat is getting ready for another set of kittens.

Queen cat’s lil kitten :

Friend cat’s lil kitten :

Lil Kitten :: Hey there human !! Got some food ? Coming down right away !!

New lil kittens :

Need to find suitable names for them 😀

Tom cat joins the show lately..

Day

Momma cat

Her face looks like wolf

Lil kittens

Aggressive momma’s aggressive kitten

He is very dominant and pick up fight with any animal including dogs when it comes to food.

Some kittens were missing as communicated by co pet care takee including Lillu 😦..

Hoping to get some info about missing cats next time.. let’s see

Lillu’s new home

Lillu got moved to new place due to some changes in current place. I got the news yesterday from my Co-pet care taker.

I visited Lillu today and heard that he was enjoying the new place very much with his fellow kittens

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Lillu eating food with new friend

This new place is home for many cats.

New momma cat

New Momma cat with her kittens

Kitten resembles queen cat.

New momma cat’s shy kitten

Young male cats

Lil kittens

Lillu

Lillu approaching new momma cat

Coming back to other cats :

Momma cat’s lil kittens searching for food

Momma cat with her kittens.Lil kittens have grown up well.

Queen cat’s lil kitten meets Scar

Everything is going well and hopefully Lillu gets adjusted to new home soon & starts new life.

When generations meet !!

Today we saw a new kitten in our office building. I bought some biscuit for her to eat in afternoon.

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In evening I met my friends near my home. I took out Lillu to meet other cats.  Lillu is growing very well under protection of Momma cat.

Lillu encounters Simba

Simba got curious of new lil kitten and checked her out. But Lillu felt threatened and scares Simba away.

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And then Lillu meets playful Jr. She hisses Lillu away.

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Lillu & Simba relaxing after eating.

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Cats : Hey Human, got any food ?

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Today was good experience for Lillu and hopefully she will get adjusted to new cats.

Momma cat’s lil kitten meets queen cat’s lil kitten.

Queen cat’s lil kitten