I am back with another article related to health & Fitness. If you have not checked my previous one on intro to fat building, please check the article in below link,
In this article, we will look in to what is insulin resistance, why it is caused, how it can be prevented.
Insulin is a hormone produced by pancreases when glucose level in blood increases. It is main anabolic ( i.e. builds body) hormone.
Purpose of Insulin
Insulin is the key factor for cells to absorb glucose for energy purpose. without insulin, body cells will be starved without food particles , leading to many health issues.
Where is Insulin produced
Pancreases is the organ that produces insulin. Endocrine tissues do this task.Pancreases also has another task related to digestion. It produces enzymes that help in digestion of food.
Insulin is produced by specific cells, called Beta cells of pancreases, when the sugar level in the blood is high. These Beta cells are sensitive to glucose concentrations. Once they detect high glucose level, they release insulin, which helps in glucose absorption by cells.
Once the glucose level is dropped in blood, these Beta cells stop producing insulin. Their neighboring alpha cells, by taking their cues from the Beta cells, secrete Glucagon ( works opposite of Insulin ) into the blood.
Once Insulin is released in to blood, it binds with cells to facilitate glucose transfer in to Muscle cells for proper functioning of cells as Glycogen. If there is any excess glucose is present, it will be saved in to Liver. Still if there is any excess glucose, it will be stored into fat cells.
Schematic two-dimensional cross-sectional view of glycogen: A core protein of glycogenin is surrounded by branches of glucose units. The entire globular granule may contain around 30,000 glucose units. Courtesy : Google.
Role of physical activity
Physical activity such as weight training/ resistance training, cardio etc. will use the glycogen stored in muscle cells & Liver. If we do work out regularly the glycogen stores gets depleted after workout and again refilled after meals. If we dont do any physical activity, the glycogen stores remain same and all the glucose entered in the blood will be stored as fat ( not good !!). This also results in fatty liver issues & Insulin Resistance
The process of Insulin secretion, food absorption by cells takes place every time we eat something. Without much physical activity , the glycogen reserves in cells remain unaffected. Therefore the cells dont need any external glucose to survive. This implies they dont need insulin for glucose transfer.
Also high carbs diets results in insulin peaks, which makes insulin to last longer in blood than normal diet. Continuously eating also results in sustained insulin levels in body. As a results cells do not respond well to insulin, as it is always present in body. So to make cells absorb glucose, excess insulin is required to make cells respond to insulin and absorb glucose. Over period this situation develops in to Type -2 Diabetics. If pancreases is unable to produce the necessary insulin for glucose transfer, it results in to type -1 diabetics.
Physical activity and proper diet helps to increase insulin sensitivity of cells. Resistance training is excellent for depleting glycogen reserves stored in muscle cells and replenish cells with proper mix of carbs, protein & fats.
Wish you a peaceful and lovely life ahead 🙂